Amitriptyline belongs to a group of medications referred to as tricyclic antidepressants (TCA) that are widely used to treat depression and other mental illnesses, such as schizophrenia and bipolar disorder. It can also be prescribed for chronic pain, migraines, pain, fibromyalgia, and insomnia. Amitriptyline works by increasing the levels of certain chemicals in the brain, which helps to improve mood. Amitriptyline is believed to re-balancing the levels of serotonin and norepinephrine, two neurotransmitters that play a big role in mood regulation.
In this blog, we explore the short-term and long-term side effects of amitriptyline and how it is used to help treat those with major depressive disorder.
What is Amitriptyline Used for?
Amitriptyline is commonly used to treat depression and other mood disorders, which to a certain extent could even include behavioral addictions. It works by modifying the levels of serotonin and norepinephrine, which helps to elevate a person’s mood. Since amitriptyline works by blocking pain signals from being sent to the brain, it provides a form of pain relief for patients.
Short-Term Side Effects
Amitriptyline is generally well-tolerated, but like all medications, it can cause side effects. The most common short-term side effects of amitriptyline are dry mouth, constipation, blurred vision, and drowsiness. Amitriptyline can also cause weight gain, although this is more likely to occur with long-term use. Less common side effects include dizziness, headache, and urinary retention.
Long-Term Side Effects
While Amitriptyline is a common medication for treating depression, it may cause a number of long-term side effects. These side effects can include constipation, weight gain, and even low blood pressure.
More serious side effects may also include seizures, irregular heartbeat, and vision problems. It is highly advised that amitriptyline should be used with caution while taking other medications, and especially for those with heart disease or a history of seizures. If you experience any of these side effects, talk to your doctor or a trained medical professional. In some instances, your doctor may even decrease your dose gradually if you experience severe symptoms.
Is Amitriptyline Addictive?
With the multiple side effects associated with taking amitriptyline, naturally one may assume amitriptyline to be addictive and should only be taken in the prescribed dose. While it is true that amitriptyline should be taken in its prescribed dosage, it is in fact, not an addictive substance.
Amitriptyline is not addictive because it does not produce the same kinds of changes in the brain that other drugs, such as cocaine or methamphetamine, do. Instead, Amitriptyline affects the brain by correcting imbalances in neurotransmitter levels rather than causing changes in the brain. Amitriptyline is also not a controlled substance, so it is not subject to the same regulations as other medications that are considered to be addictive.
Amitriptyline Dosage
Amitriptyline is a prescription medication and all dosages are prescribed by a medical professional. However, you may be prescribed higher or lower doses depending on the individual’s response to the medication. If a dose is missed, it should be taken as soon as possible. However, if it is almost time for the next dose, the missed dose should be skipped and the regular dosing schedule resumed. Taking more than one dose at a time can increase the risk of side effects.
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